September 6 is the 249th day of the year. 116 days remain until the end of the year.
- 1666 – Ivan V of Russia, Russian tsar (d. 1696)
- 1757 – Gilbert du Motier, Marquis de Lafayette, French general (d. 1834)
- 1819 – William Rosecrans, American general, politician, and diplomat, United States Ambassador to Mexico (d. 1898)
- 1888 – Joseph P. Kennedy Sr., American businessman and diplomat, 44th United States Ambassador to the United Kingdom (d. 1969)
- 1954 – Carly Fiorina, American businesswoman and activist
- 1958 – Jeff Foxworthy, American comedian, actor, producer, and screenwriter
- 1983 – Braun Strowman, American wrestler and strongman
- 952 – Suzaku, emperor of Japan (b. 923)
- 972 – John XIII, pope of the Catholic Church (b. 930)
- 1945 – John S. McCain Sr., American admiral (b. 1884)
- 2012 – Art Modell, American businessman (b. 1925)
- 2018 – Burt Reynolds, American actor, director and producer (b. 1936)
- 1492 – Christopher Columbus sails from La Gomera in the Canary Islands, his final port of call before crossing the Atlantic Ocean for the first time.
- 1522 – The Victoria returns to Sanlúcar de Barrameda in Spain, the only surviving ship of Ferdinand Magellan’s expedition and the first ship to circumnavigate the world.
- 1620 – The Pilgrims sail from Plymouth, England on the Mayflower to settle in North America. (Old Style date; September 16 per New Style date.)
- 1628 – Puritans settle Salem which became part of Massachusetts Bay Colony.
- 1901 – Leon Czolgosz, an unemployed anarchist, shoots and fatally wounds US President William McKinley at the Pan-American Exposition in Buffalo, New York.
- 1916 – The first self-service grocery store Piggly Wiggly was opened in Memphis, Tennessee by Clarence Saunders.
- 1946 – United States Secretary of State James F. Byrnes announces that the U.S. will follow a policy of economic reconstruction in postwar Germany.
- 1968 – Swaziland becomes independent.
- 1970 – Two passenger jets bound from Europe to New York are simultaneously hijacked by Palestinian terrorist members of the PFLP and taken to Dawson’s Field, Jordan.
- 1972 – Munich massacre: Nine Israeli athletes die (along with a German policeman) at the hands of the Palestinian “Black September” terrorist group after being taken hostage at the Munich Olympic Games. Two other Israeli athletes were slain in the initial attack the previous day.
- 1991 – The Russian parliament approves the name change of Leningrad back to Saint Petersburg. The change is effective October 1, 1991.
- 1995 – Cal Ripken, Jr. of the Baltimore Orioles plays in his 2,131st consecutive game, breaking a record that had stood for 56 years.
- 1997 – The Funeral of Diana, Princess of Wales takes place in London. Well over a million people lined the streets and 21⁄2 billion watched around the world on television.
- Barbie Doll Day
- Fight Procrastination Day
- National Coffee Ice Cream Day
- Great Egg Toss Day
- National 401(k) Day
- National Food Bank Day
- National Lazy Mom’s Day
- Read a Book Day
- Stillbirth Remembrance Day
- Wear Teal Day